
Guido
Please meet our handsome mahogany boy GUIDO. His coloring is the rarest in the Neapolitan Mastino Breed. Guido and Gino were found roaming in Texas mo…
Mastino Rescue, Inc. • St. Charles, MO
6 adoptable Neapolitan Mastiff dogs from shelters and rescues in Missouri.
Every Neapolitan Mastiff here is a real dog currently listed for adoption by a shelter or rescue in Missouri. Listings are refreshed regularly, but availability changes fast — always confirm with the organization before making plans.
6 Neapolitan Mastiff dogs in Missouri

Please meet our handsome mahogany boy GUIDO. His coloring is the rarest in the Neapolitan Mastino Breed. Guido and Gino were found roaming in Texas mo…
Mastino Rescue, Inc. • St. Charles, MO

Amara is a stunning blue girl, ~20 months old, who came to rescue from a home in rural Northwest Arkansas. With the help of our amazing rescue partner…
Mastino Rescue, Inc. • St. Charles, MO

Our Royal Mastino, Livia, is doing well in her experienced foster home, but continues to dream of a family and home of her own. Princess Livia (as she…
Mastino Rescue, Inc. • St. Charles, MO

Miss Anita found herself abandoned in her owner's garage when they moved. Several neighbors rallied around her to help her find a new home and family.…
Mastino Rescue, Inc. • St. Charles, MO

Gracie came to us from an Arkansas Shelter basically at the same time as Adolfo. She was also severely underweight and heartworm positive. Gracie has …
Mastino Rescue, Inc. • St. Charles, MO

Adolfo came to us after being surrendered to an Arkansas shelter. He is currently being boarded in Missouri and is a VERY active and playful boy. He i…
Mastino Rescue, Inc. • St. Charles, MO
Open any dog's profile to see which shelter or rescue is caring for them in Missouri, then follow the adoption link or contact details to apply directly with that organization. Every Dog's Chance gathers listings in one place so they're easier to find — the adoption itself happens through the local shelter or rescue.
Many Neapolitan Mastiff dogs — especially adults who are already house-trained — can be a great match for first-time owners. Each dog's profile and the shelter or rescue caring for them can tell you about that individual dog's energy level, training history, and personality before you apply.
Adoption fees vary by shelter and rescue in Missouri, but typically include spay/neuter, vaccinations, and a health check. Open any dog's profile and contact the organization directly for their current fee and what it covers.
Yes. Most shelters and rescues in Missouri welcome adopters from anywhere in the state, and some can arrange transport for the right match. Open a dog's profile to see the organization's contact details and ask them how their process works.
Many shelters and rescues in Missouri offer foster programs, sometimes with a foster-to-adopt path so you can see if the match feels right before committing. Ask the organization on any dog's profile whether fostering is available.
It depends on the individual dog more than the breed alone. The shelter or rescue caring for each dog can tell you about their history with kids, cats, and other dogs. Many organizations offer meet-and-greets to make sure the match is right for everyone before you commit.