
Luna Dale
BONDED WITH STELLA BRENNAN, A142659. MUST BE ADOPTED TOGETHER AND KEPT TOGETHER.Super sweet girls. We think LUNA DALE might be mom. They are strong bu…
Burbank Animal Shelter • Burbank, CA
11 adoptable dogs from shelters and rescues across the US.
Neapolitan Mastiff dogs come in all stages — playful puppies still learning the world, energetic adults ready for adventure, and calmer companions who are house-trained and happy to curl up beside you. All listings shown here are real Neapolitan Mastiff dogs currently available from shelters and rescues across the US. Confirm availability directly with the shelter or rescue before applying.
11 Neapolitan Mastiff dogs available

BONDED WITH STELLA BRENNAN, A142659. MUST BE ADOPTED TOGETHER AND KEPT TOGETHER.Super sweet girls. We think LUNA DALE might be mom. They are strong bu…
Burbank Animal Shelter • Burbank, CA

BONDED WITH LUNA DALE, A142661. MUST BE ADOPTED TOGETHER AND KEPT TOGETHER.Super sweet girls. We think Luna Dale might be mom. They are strong but lov…
Burbank Animal Shelter • Burbank, CA

Ghost is a big boy with an even bigger heart. This handsome Neapolitan Mastiff/Great Dane mix is 5 years old and over 108 lbs, but don’t let his size …
Eleventh Hour Rescue • Rockaway, NJ

Please meet our handsome mahogany boy GUIDO. His coloring is the rarest in the Neapolitan Mastino Breed. Guido and Gino were found roaming in Texas mo…
Mastino Rescue, Inc. • St. Charles, MO

Amara is a stunning blue girl, ~20 months old, who came to rescue from a home in rural Northwest Arkansas. With the help of our amazing rescue partner…
Mastino Rescue, Inc. • St. Charles, MO

Our Royal Mastino, Livia, is doing well in her experienced foster home, but continues to dream of a family and home of her own. Princess Livia (as she…
Mastino Rescue, Inc. • St. Charles, MO

Miss Anita found herself abandoned in her owner's garage when they moved. Several neighbors rallied around her to help her find a new home and family.…
Mastino Rescue, Inc. • St. Charles, MO

Gracie came to us from an Arkansas Shelter basically at the same time as Adolfo. She was also severely underweight and heartworm positive. Gracie has …
Mastino Rescue, Inc. • St. Charles, MO

Adolfo came to us after being surrendered to an Arkansas shelter. He is currently being boarded in Missouri and is a VERY active and playful boy. He i…
Mastino Rescue, Inc. • St. Charles, MO


Open any dog's profile to see the shelter or rescue caring for them, then use the adoption link or contact details to apply directly with that organization. Every Dog's Chance simply gathers listings in one place so they're easier to find.
Many Neapolitan Mastiff dogs — especially adult dogs who are already house-trained — can be a great match for first-time owners. Each dog's profile and the shelter or rescue caring for them can tell you about that dog's individual energy level, training, and personality before you apply.
Adoption fees vary by shelter and rescue, but typically include spay/neuter, vaccinations, and a health check. Open any dog's profile and contact the organization directly for their current fee and what it covers.
It depends on the individual dog more than the breed alone. The shelter or rescue caring for each dog can tell you about their history with kids, cats, and other dogs. Many organizations offer meet-and-greets to make sure the match is right for everyone before you commit.
Many shelters and rescues offer a foster program, sometimes with a foster-to-adopt path. Fostering a Neapolitan Mastiff gets them out of a kennel and into a calm home, which is a great way to see if the match feels right before committing. Ask the organization on any dog's profile whether fostering is an option.
Most dogs have a brief adjustment period — a few days to a couple of weeks — as they settle into a new home. A consistent routine, a comfortable place to rest, and patience make the transition easier for both of you. The shelter or rescue can tell you what to expect from the specific dog you're adopting.