165 adoptable dogs from shelters and rescues across the US. Showing 61–90 of 165 below.
Standing taller than most kitchen counters, the Great Dane is a gentle, sensitive giant that would rather lean on you than guard you. Danes are affectionate, a little goofy, and surprisingly calm indoors. They reach shelters because of size, cost, and housing restrictions rather than temperament.
A Dane puppy grows at an astonishing pace, and that growth needs to be protected. No forced running, no stair marathons, and careful feeding until the skeleton matures. Training should start young, because a dog that pulls or jumps at this size is a genuine safety issue. Adults are usually mellow, content with a couple of moderate walks and a soft bed. They are not built for long runs.
Bloat is the single most important health topic, along with hips, heart conditions, and bone problems, and all of these are things to ask the shelter and your veterinarian about. Danes are sensitive to harsh correction and do best with a calm, steady owner. They need room to turn around, a vehicle they fit in, and a budget for a big dog. Ask the shelter or rescue what this Dane has lived through, how he does alone, and what training he has picked up so far.
165 Great Dane dogs available — page 3 of 6
Meet Oscar DooLocation: Denham Springs, LADOB: 4/19/24Oscar Doo is a sweet, lovable boy with a heart full of affection and a strong desire to be close…
SRGDRR Inc aka Save Rocky the Great Dane Rescue and Rehab • Bullard, TX
Toasted Marshmallow is the full government name, but my foster mom calls me Toast, Toaster, Toaster Waffle, Toasty Marshy, and Derpy Dude. I love my f…
Adopt A Pit Rescue Inc • Germantown, OH
SRGDRR Inc aka Save Rocky the Great Dane Rescue and Rehab • Bullard, TX
SCOOBYIs an energetic and enthusiastic boy. He continues working on his leash skills with our amazing volunteers and staff. He does well with other do…
Humboldt County Sheriff's Animal Shelter • McKinleyville, CA
Randolph County Humane Society • Elkins, WV
SRGDRR Inc aka Save Rocky the Great Dane Rescue and Rehab • Bullard, TX
Please go to our website for all specific information about this dog. Our info doesn't transfer over to the adoption sites. Scooby was owned by the fa…
Collar of Hope • Olalla, WA
Gertrude is a 2 year old spayed female. She is a very affectionate girl she is now a socialized girl. She is a little shy at first. She is good with o…
Great Dane Rescue of South Florida • Palm Beach, FL
Hi, my name is Duke, aka Dukie Boy. Folks think I’m part Great Dane, GSD, hound, and just an overall big Heinz 57! I’m a bit over 100 lbs. and am a gr…
Adopt A Pit Rescue Inc • Germantown, OH
Name: TimothyBreed? Great dane mix with labrador Age: 5 years old as per shelterVaccines: UTD YESMedical conditions: NoNeautured: YesChip: YesTemperam…
Paws 4 You Rescue • Miami, FL
SRGDRR Inc aka Save Rocky the Great Dane Rescue and Rehab • Bullard, TX
Meet Hank! He’s a 5 year old Great Dane with some allergies. So, we’ll be hooking him up with some farm eggs & salmon kibble. Can’t wait to snuggle th…
Community Animal Rescue Effort (CARE) • Columbus, IN
THIS PET IS A FOUND PET**Date Found: 3/18/26Location Found: 6th/CentralStatus of Pet: In FINDERS HomeMicrochip Status: scanned, no chip**This pet is w…
City of Tracy Animal Services • Tracy, CA
Mia was born about August 20, 2025 and will likely top out in the 125 weight range with the possibility of less or more. Mia is somewhat timid at firs…
Joyful Rescues, Inc. • Cuba, NY
Thank you for considering adopting a Rescue Ranch dog. While they are with us, each and every rescue dog receives the best of care in a loving and nur…
Rescue Ranch • Yreka, CA
Gracie is the best girl. She came to us extremely skinny and nervous, but has blossomed into an amazing companion, over the past few months, as we hav…
Pregnant Dog And All Breed Rescue • Newfoundland, PA
DOB: 3/27/2023 Weight: 80 lbs. Alfie is a handsome 3-year-old Great Dane/Poodle mix with a big heart and an even bigger personality. He is neutered, m…
Legacy Humane Society • McKinney, TX
This is a courtesy post. Please do not contact Heart of the Foothills for information. Please email the owner at meganmaglione@yahoo.com(704) 619-3895…
Heart of the Foothills Animal Rescue • Rutherfordton, NC
Looking for a guy with beauty AND brains? I'm Caleb, and behind this devilishly handsome, merle face, you will find THE biggest brain. I know sit, paw…
Marion County Animal Services • Ocala, FL
Meet Max: The 90lb Lap Dog You Didn't Know You Needed! Hi there! I’m Max, a big, goofy, high-energy Lab looking for my forever adventure buddy. I abso…
Rescue Ranch • Yreka, CA
Scooby had a rough life. He was found as a stray in Leavenworth County. We believe he is around 4 to 5 years old and is a great Dane mix. He is very s…
Riverview Rescue • Leavenworth, KS
Meet Ember (115D)Location: Granbury, TXDate of Birth: May 1, 2021Good with other dogs; cats unknownEmber is a loyal, affectionate, and intelligent dog…
SRGDRR Inc aka Save Rocky the Great Dane Rescue and Rehab • Bullard, TX
Meet Chevy Status: Available Sex: Spayed Female – Gastropexied Color: Merle Ears: Natural Age: 6 yrs Weight: 108 lbs Great Dane Experience Required Ad…
Rocky Mountain Great Dane Rescue • Lakewood, CO
Wallen is a charming three-year-old Great Dane mix who tips the scales at a healthy 62 pounds. Wallen is the epitome of sweetness, always ready to sho…
Hilton Head Humane Association • Hilton Head, SC
Molly is such a beautiful large breed girl who is searching for a family. Molly was born in October of 2024 and does well with other dogs and has a gr…
Benevolent Animal Rescue Committee, Inc • Cherry Valley, CA
Name: Lucy Age: 2 years Weight: 95 lbs Adoption Fee: $350.00 Good with Dogs? Yes, but she can be a little pushy so a mellow dog would be okay Good wit…
PawPrints Animal Rescue Inc • Florence, KY
Less than most people think, but more than a studio apartment. Danes are calm indoors and spend much of the day lying down, so a modest home works if the dog gets daily walks. What they need is room to stretch out, a bed that fits, and a car that can carry them.
Generally yes, and often wonderful. They are patient and gentle by nature. The hazard is accidental. A tail at toddler head height or a happy lean can knock a small child down. Families with older children or careful supervision tend to do well. Ask the shelter about this dog's history with kids.
Bloat, a sudden twisting of the stomach, is the emergency to learn about. Heart disease, hip issues, and bone problems in growing puppies also come up. Ask the shelter for any medical record and talk with your veterinarian early about feeding and exercise routines that reduce risk.
Open any dog's profile to see the shelter or rescue caring for them, then use the adoption link or contact details to apply directly with that organization. Every Dog's Chance simply gathers listings in one place so they're easier to find.
Many Great Dane dogs — especially adult dogs who are already house-trained — can be a great match for first-time owners. Each dog's profile and the shelter or rescue caring for them can tell you about that dog's individual energy level, training, and personality before you apply.
Adoption fees vary by shelter and rescue, but typically include spay/neuter, vaccinations, and a health check. Open any dog's profile and contact the organization directly for their current fee and what it covers.
It depends on the individual dog more than the breed alone. The shelter or rescue caring for each dog can tell you about their history with kids, cats, and other dogs. Many organizations offer meet-and-greets to make sure the match is right for everyone before you commit.
Many shelters and rescues offer a foster program, sometimes with a foster-to-adopt path. Fostering a Great Dane gets them out of a kennel and into a calm home, which is a great way to see if the match feels right before committing. Ask the organization on any dog's profile whether fostering is an option.
Most dogs have a brief adjustment period — a few days to a couple of weeks — as they settle into a new home. A consistent routine, a comfortable place to rest, and patience make the transition easier for both of you. The shelter or rescue can tell you what to expect from the specific dog you're adopting.
