Mastiff Dogs for Adoption

266 adoptable dogs from shelters and rescues across the US. Showing 121–150 of 266 below.

About adopting a Mastiff

"Mastiff" on a shelter listing is a broad label. It can mean an English Mastiff, a Bullmastiff, a Neapolitan, a Cane Corso, or simply a very large dog with a heavy head and loose lips whose background nobody knows. Shelter staff assign it based on what a dog looks like at intake, so the word describes a body type more than a pedigree.

What the label tends to predict is size and a calm, watchful manner. Many mastiff-type dogs are quiet in the house, slow to react, and deeply attached to their people. Puppies under this label grow fast and stay clumsy for a long stretch, so early training pays off. Adults are often already past the wild stage and settle into a routine quickly.

What the label cannot tell you is how a particular dog feels about strangers, other dogs, or being left alone. Guarding instincts run through several of the breeds grouped here and show up differently in each individual. Drool, snoring, and a big food bill come with most of them. Hip and joint concerns, bloat, and heat sensitivity are things to ask the shelter and your veterinarian about. Ask the shelter or rescue what this dog has lived through and what training he has had so far, because that matters more than the word on the card.

266 Mastiff dogs available — page 5 of 9

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Photo of Paco, adoptable Mastiff in Moreno Valley, California

Paco

Mastiff MaleLarge1 year

Paco knows sit and shake* Paco appears to be potty trained* Paco loves toys* Paco enjoys sharing a kennel with a spayed Chinese Sharpei mix, they pref…

Moreno Valley Animal Shelter • Moreno Valley, CA

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Photo of Atlas, adoptable Mastiff in Amarillo, Texas

Atlas

Mastiff MaleLargeYoung

Atlas is a male Mastiff mix. He was brought in by Randall County Sheriff's Dept. This is a large dog, who appears to be at least 1 year of age, and qu…

Amarillo SPCA • Amarillo, TX

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Photo of Daisy #27, adoptable Mastiff in Chandler, Arizona

Daisy #27

Mastiff FemaleX-Large3 years

Please note this dog is NOT an official Underdog dog, and you will be connected with the person who has the dog. Please Contact (Current Owner of Dog)…

Underdog Rescue of Arizona, LLC • Chandler, AZ

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Photo of Ruby, adoptable Mastiff in Sequim, Washington

Ruby

Mastiff FemaleLarge0 years

Meet Ruby! Ruby came to WAG after being rescued from a house fire as a young puppy, and she has grown into a joyful adolescent with plenty of personal…

Welfare for Animals Guild • Sequim, WA

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Photo of Penny, adoptable Mastiff in Alameda, California

Penny

Mastiff FemaleLarge2 years

• Loves affection• Playful, great to walk• Super splasherPenny arrived to us unsure of the world, but has since decided that after careful considerati…

Friends of the Alameda Animal Shelter • Alameda, CA

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Photo of Baloo, adoptable Mastiff in Roswell, Georgia

Baloo

Mastiff MaleLarge1 year

HI, I'M BALOO! I LOVE KIDS AND OTHER DOGS. IF YOU'D LIKE TO ADOPT ME, PLEASE FILL OUT THE APPLICATION AT WWW.BARKVILLEDOGRESCUE.ORG/APPLICATIONS OR SE…

Barkville Dog Rescue • Roswell, GA

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Photo of Jello, adoptable Mastiff in Princeton, Minnesota

Jello

Mastiff MaleX-Large0 years

Jello is very sweet, laid back, and quiet, with a playful side that comes out once he’s comfortable. He’s the definition of go-with-the-flow and is kn…

Ruff Start Rescue • Princeton, MN

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Photo of Maisy, adoptable Mastiff in Edmond, Oklahoma

Maisy

MastiffX-Large5 years

Meet Maisy! This beautiful girl was rescued by a small all-breed rescue in rural Texas, emaciated and late term pregnant. They reached out to GPMR and…

Great Plains Mastiff Rescue Foundation • Edmond, OK

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Photo of Rollie #2, adoptable Mastiff in Chandler, Arizona

Rollie #2

Mastiff MaleLarge3 years

Please note this dog is NOT an official Underdog dog, and you will be connected with the person who has the dog. Please Contact Wendy, 602-818-5541, I…

Underdog Rescue of Arizona, LLC • Chandler, AZ

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Photo of Magnum, adoptable Mastiff in Chandler, Arizona

Magnum

Mastiff MaleLarge2 years

Please note this dog is NOT an official Underdog dog, and you will be connected with the person who has the dog. Please Contact (Current Owner of Dog)…

Underdog Rescue of Arizona, LLC • Chandler, AZ

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Photo of Bruno, adoptable Mastiff in Edmond, Oklahoma

Bruno

Mastiff MaleX-Large1 year

Meet Bruno! This handsome boy came into rescue when his owners were having a baby and felt like they weren't able to give him the time he deserved. We…

Great Plains Mastiff Rescue Foundation • Edmond, OK

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Photo of Garcia, adoptable Mastiff in Catasauqua, Pennsylvania

Garcia

Mastiff MaleLarge0 years

Meet Garcia Garcia is truly a survivor. He came to us from the brink of starvation and has fought his way back to health, confidence, and purpose. Now…

Outcast Rescue • Catasauqua, PA

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Photo of Mirabelle, adoptable Mastiff in Edmond, Oklahoma

Mirabelle

Mastiff FemaleX-Large5 years

Meet Mirabelle, the miracle! This amazing girl was surrendered to local animal control from a neglect situation. Sadly she recently had puppies that w…

Great Plains Mastiff Rescue Foundation • Edmond, OK

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Photo of Pocket, adoptable Mastiff in Bandera, Texas

Pocket

Mastiff FemaleLarge0 years

Welcome Pocket to CCPAL Rescue. Pocket is a 4.5 month old Mastiff/Great Pyrenees. Pocket is extremely affectionate and stunningly beautiful. This whol…

Cowboy Capital Pet Assistance League • Bandera, TX

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Photo of Barron, adoptable Mastiff in Bandera, Texas

Barron

Mastiff MaleLarge0 years

Welcome Barron to CCPAL Rescue. Barron is a 4.5 month old Mastiff/Great Pyrenees. Barron is extremely affectionate and stunningly beautiful. This whol…

Cowboy Capital Pet Assistance League • Bandera, TX

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Photo of Jimbo, adoptable Mastiff in Yreka, California

Jimbo

Mastiff MaleLarge5 years

Meet Jimbo! Jimbo is a big, lovable sweetheart who’s new to our crew — and he’s already stealing hearts left and right! This handsome boy absolutely a…

Rescue Ranch • Yreka, CA

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Photo of clifford, adoptable Mastiff in Shreveport, Louisiana

clifford

Mastiff Male3 years

Clifford the big black dog is a beautiful massive dog! He is BIG and his personality is just as BIG! This guy has been a joy, he is a happy playful gu…

Saved By Grace Animal Rescue • Shreveport, LA

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Photo of Eden, adoptable Mastiff in Waco, Texas

Eden

Mastiff FemaleLarge4 years

Humane Society of Central Texas/City of Waco Animal Shelter • Waco, TX

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Photo of Moose, adoptable Mastiff in Lake Forest, California

Moose

Mastiff MaleX-Large2 years

This handsome big guy is Moose, a sweet 2-year-old pup tipping the scales at 97 lbs of love! Moose has had lots of training under his belt and is full…

The Little Red Dog, Inc • Lake Forest, CA

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Photo of Nema, adoptable Mastiff in Savannah, Missouri

Nema

Mastiff FemaleLarge5 years

Hi, my name is Nema. I'm a friendly girl but a little on the shy side. But, I do warm up quickly. I love people. Although, not all people have been go…

M'Shoogy's Famous Emergency Animal Rescue • Savannah, MO

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Photo of Odin, adoptable Mastiff in Poplar Bluff, Missouri

Odin

Mastiff MaleLarge6 years

Odin is a mastiff mix weighing in around 100 pounds. He is up to date on vaccinations and neutered. He is great with people and lived with several chi…

Hearts for Rescue • Poplar Bluff, MO

Adopting a Mastiff — FAQ

Is a Mastiff a good family dog?

Many mastiff-type dogs are gentle and patient with their own family, and their calm nature suits a quiet home. Their size means a wagging tail or a friendly lean can knock over a toddler, so supervision matters. Early socialization and clear house rules help a young dog grow into a steady adult.

How much exercise does a Mastiff need?

Less than most people expect. A couple of steady walks and some time to sniff around a yard satisfy most adults. Puppies should not be run hard or taken on long hikes while their joints are still developing. Mental work, like short training sessions, tires them out just as well.

Why do so many Mastiffs end up in shelters?

Size is the most common reason. A dog that seemed manageable as a puppy becomes expensive to feed, hard to house in a rental, and difficult to move. Some families also underestimate the drool and shedding. Very few are surrendered for aggression, and many arrive already house trained and mellow.

How do I adopt a Mastiff?

Open any dog's profile to see the shelter or rescue caring for them, then use the adoption link or contact details to apply directly with that organization. Every Dog's Chance simply gathers listings in one place so they're easier to find.

Are Mastiff dogs a good fit for first-time adopters?

Many Mastiff dogs — especially adult dogs who are already house-trained — can be a great match for first-time owners. Each dog's profile and the shelter or rescue caring for them can tell you about that dog's individual energy level, training, and personality before you apply.

How much does it cost to adopt a Mastiff?

Adoption fees vary by shelter and rescue, but typically include spay/neuter, vaccinations, and a health check. Open any dog's profile and contact the organization directly for their current fee and what it covers.

Are Mastiff dogs good with children or other pets?

It depends on the individual dog more than the breed alone. The shelter or rescue caring for each dog can tell you about their history with kids, cats, and other dogs. Many organizations offer meet-and-greets to make sure the match is right for everyone before you commit.

Can I foster a Mastiff instead of adopting?

Many shelters and rescues offer a foster program, sometimes with a foster-to-adopt path. Fostering a Mastiff gets them out of a kennel and into a calm home, which is a great way to see if the match feels right before committing. Ask the organization on any dog's profile whether fostering is an option.

What should I expect in the first weeks after adopting a Mastiff?

Most dogs have a brief adjustment period — a few days to a couple of weeks — as they settle into a new home. A consistent routine, a comfortable place to rest, and patience make the transition easier for both of you. The shelter or rescue can tell you what to expect from the specific dog you're adopting.