Mastiff Dogs for Adoption
266 adoptable dogs from shelters and rescues across the US. Showing 211–240 of 266 below.
About adopting a Mastiff
"Mastiff" on a shelter listing is a broad label. It can mean an English Mastiff, a Bullmastiff, a Neapolitan, a Cane Corso, or simply a very large dog with a heavy head and loose lips whose background nobody knows. Shelter staff assign it based on what a dog looks like at intake, so the word describes a body type more than a pedigree.
What the label tends to predict is size and a calm, watchful manner. Many mastiff-type dogs are quiet in the house, slow to react, and deeply attached to their people. Puppies under this label grow fast and stay clumsy for a long stretch, so early training pays off. Adults are often already past the wild stage and settle into a routine quickly.
What the label cannot tell you is how a particular dog feels about strangers, other dogs, or being left alone. Guarding instincts run through several of the breeds grouped here and show up differently in each individual. Drool, snoring, and a big food bill come with most of them. Hip and joint concerns, bloat, and heat sensitivity are things to ask the shelter and your veterinarian about. Ask the shelter or rescue what this dog has lived through and what training he has had so far, because that matters more than the word on the card.
266 Mastiff dogs available — page 8 of 9
Gisele
Affectionate · Calm · Does well in social environments (outside of the home) · Does well in the car · Eager to Please · Food Motivated · Friendly/soci…
Freedom Ride Rescue • Raleigh area, NC
Ruby
Health Waiver · Text 440-376-7995 (Kristen) to set up a meet and greet
Berea Animal Rescue Friends • Berea, OH
Squeakers
Maricopa County Animal Care & Control - West Valley Animal Care Center • Phoenix, AZ
Coco
Coco is a 6-month-old Pit Bull mix who can be a little shy when she first meets you, especially here at the shelter. But give her a little time and sh…
Beaver County Humane Society • Center Township, PA
Mr. Boofer
The Animal Foundation - Las Vegas • Las Vegas, NV
Dante
Meet Dante, a gentle giant Mastiff who is ready to find his forever home! At 5 years old, this calm and affectionate neutered male is a true sweethear…
City of Tulsa Animal Welfare • Tulsa, OK
Tokyo
City of Corpus Christi Animal Care • Corpus Christi, TX
Beaver
The Animal Foundation - Las Vegas • Las Vegas, NV
Luna
Anchorage Animal Care and Control • Anchorage, AK
Simbalucci
Hi there! My name is Simbalucci, but my foster family lovingly calls me Stanley Tucci, and I can't wait to meet you! I'm a sweet, friendly guy with a …
Montgomery County Animal Services and Adoption Center • Derwood, MD
Red
06/21/26 12:05Looking for a sweet boy to call your own? Meet Red! Red is a shy 1 year old that has been at the shelter since May. This gentle dog is k…
San Jose Animal Care Center • San Jose, CA
Riley
Hey there! My name is Riley. I am a one-year-old Mastiff mix. I am just asweet, happy-go-lucky girl with a forever wagging tail. I am just a ray ofsun…
Miami Dade Animal Services • Miami, FL
Heath
Meet Heath!! Heath is 8 weeks old and one big, squishy bundle of puppy love! This chunky little guy has the cutest fat puppy belly, big paws, and an e…
Adopt A Dog Rescue • Phoenix, AZ
A170459
Bakersfield Animal Care Center • Bakersfield, CA
Enzo
2 year old boy looking forward to a new forever family. Good with dogs.
Don't Bully Us Rescue • Wenonah, NJ
Gloria
Grand Prairie Animal Services • Grand Prairie, TX
Cooper
COOPER Cooper has come into Rescue with his sister, Lulu. They are a bonded pair and will be adopted together
Mastiff Rescue Oregon • McMinnville, OR
lulu
LULU Lulu has come into Rescue with her brother, Cooper They are a bonded pair and will be adopted together
Mastiff Rescue Oregon • McMinnville, OR
Gully
Maricopa County Animal Care & Control - West Valley Animal Care Center • Phoenix, AZ
Rowan
Personality: playful, curious Breed: mastiff mix Age: est DOB 11/11/25 Weight: 70lbs and growing Sex: male Rescued from Tehama County Large, cl…
Coppers Dream • Sunnyvale, CA
Carl
View this post on Instagram A post shared by City of San Bernardino Department of Animal Services (@sbcitypets)
San Bernardino City Animal Control • San Bernardino, CA
Gideon
Maricopa County Animal Care & Control - West Valley Animal Care Center • Phoenix, AZ
Mastiff dogs by state
Other breeds
Adopting a Mastiff — FAQ
Is a Mastiff a good family dog?
Many mastiff-type dogs are gentle and patient with their own family, and their calm nature suits a quiet home. Their size means a wagging tail or a friendly lean can knock over a toddler, so supervision matters. Early socialization and clear house rules help a young dog grow into a steady adult.
How much exercise does a Mastiff need?
Less than most people expect. A couple of steady walks and some time to sniff around a yard satisfy most adults. Puppies should not be run hard or taken on long hikes while their joints are still developing. Mental work, like short training sessions, tires them out just as well.
Why do so many Mastiffs end up in shelters?
Size is the most common reason. A dog that seemed manageable as a puppy becomes expensive to feed, hard to house in a rental, and difficult to move. Some families also underestimate the drool and shedding. Very few are surrendered for aggression, and many arrive already house trained and mellow.
How do I adopt a Mastiff?
Open any dog's profile to see the shelter or rescue caring for them, then use the adoption link or contact details to apply directly with that organization. Every Dog's Chance simply gathers listings in one place so they're easier to find.
Are Mastiff dogs a good fit for first-time adopters?
Many Mastiff dogs — especially adult dogs who are already house-trained — can be a great match for first-time owners. Each dog's profile and the shelter or rescue caring for them can tell you about that dog's individual energy level, training, and personality before you apply.
How much does it cost to adopt a Mastiff?
Adoption fees vary by shelter and rescue, but typically include spay/neuter, vaccinations, and a health check. Open any dog's profile and contact the organization directly for their current fee and what it covers.
Are Mastiff dogs good with children or other pets?
It depends on the individual dog more than the breed alone. The shelter or rescue caring for each dog can tell you about their history with kids, cats, and other dogs. Many organizations offer meet-and-greets to make sure the match is right for everyone before you commit.
Can I foster a Mastiff instead of adopting?
Many shelters and rescues offer a foster program, sometimes with a foster-to-adopt path. Fostering a Mastiff gets them out of a kennel and into a calm home, which is a great way to see if the match feels right before committing. Ask the organization on any dog's profile whether fostering is an option.
What should I expect in the first weeks after adopting a Mastiff?
Most dogs have a brief adjustment period — a few days to a couple of weeks — as they settle into a new home. A consistent routine, a comfortable place to rest, and patience make the transition easier for both of you. The shelter or rescue can tell you what to expect from the specific dog you're adopting.
